Am J Med Genet A

We report on a girl with delayed mental and motor development, ophthalmological abnormalities, and peripheral neuropathy. Chromosome analysis suggested a deletion within chromosome 8p. Further investigation by array-based comparative genomic hybridization (array-CGH) delineated an 8 Mb interstitial deletion on the short arm of chromosome 8. The breakpoints are located at chromosome bands 8p12 and 8p21.2. Forty-two known genes including gonadotropin-releasing hormone 1 (GNRH1), transcription factor EBF2, exostosin-like 3 (EXTL3), glutathione reductase (GSR), and neuregulin 1 (NRG1), are located within the deleted region on chromosome 8p. A comparison of our patient with the cases described in the literature is presented, and we discuss the genotype-phenotype correlation in our patient. This is the first report of array-CGH analysis of an interstitial deletion at chromosome 8p

Social trajectories or disrupted identities? : Changing and competing models of teacher professionalism under New Labour

Since the 1988 Education Reform Act, the teacher’s role in England has changed in many ways, a process which intensified under New Labour after 1997. Conceptions of teacher professionalism have become more structured and formalized, often heavily influenced by government policy objectives. Career paths have become more diverse and specialised. In this article, three post-1997 professional roles are given consideration as examples of these new specialised career paths: Higher Level Teaching Assistants, Teach First trainees and Advanced Skills Teachers. The article goes on to examine such developments within teaching, using Bourdieu’s concept of habitus to inform the analysis, as well as Bernstein’s theories of knowledge and identity. The article concludes that there has been considerable specialization and subsequent fragmentation of roles within the teaching profession, as part of workforce remodelling initiatives. However, there is still further scope for developing a greater sense of professional cohesion through social activism initiatives, such as the children's agenda. This may produce more stable professional identities in the future as the role of teachers within the wider children’s workforce is clarified

Place attachment in deprived neighbourhoods: The impacts of population turnover and social mix

This paper examines the determinants of individual place attachment, focussing in particular on differences between deprived and others neighbourhoods, and on the impacts of population turnover and social mix. It uses a multi-level modelling approach to take account of both individual- and neighbourhood-level determinants. Data are drawn from a large sample government survey, the Citizenship Survey 2005, to which a variety of neighbourhood-level data have been attached. The paper argues that attachment is significantly lower in more deprived neighbourhoods primarily because these areas have weaker social cohesion but that, in other respects, the drivers of attachment are the same. Turnover has modest direct impacts on attachment through its effect on social cohesion. Social mix has very limited impacts on attachment and the effects vary between social groups. In general, higher status or more dominant groups appear less tolerant of social mix

Citizens without nations

To broach the question of whether citizenship could exist without (or beyond) community, this paper discusses genealogies of citizenship as membership that binds an individual to the community of birth (of the self or a parent). It is birthright as fraternity that blurs the boundary between citizenship and nationality. After briefly discussing recent critical studies on birthright citizenship (whether it is civic or ethnic or blood or soil) by Ayelet Shachar and Jacqueline Stevens, the paper discusses three critical genealogies of the relationship between birthright and citizenship by Max Weber, Hannah Arendt, and Michel Foucault. Although each provides a critical perspective into the question, Weber reduces citizenship to fraternity with nation and Arendt reduces citizenship to fraternity with the state. It is Foucault who illustrates racialization of fraternity as the connection between citizenship and nationality. Yet, since Foucault limits his genealogical investigations to the 18th and 19th centuries, a genealogy of fraternity of what he calls an immense biblical and Greek tradition remains for Derrida to articulate as a question of citizenship

Culture and personality revisited: Behavioral profiles and within‐person stability in interdependent (vs. independent) social orientation and holistic (vs. analytic) cognitive style

ObjectiveWe test the proposition that both social orientation and cognitive style are constructs consisting of loosely related attributes. Thus, measures of each construct should weakly correlate among themselves, forming intraindividually stable profiles across measures over time.MethodStudy 1 tested diverse samples of Americans (N = 233) and Japanese (N = 433) with a wide range of measures of social orientation and cognitive style to explore correlations among these measures in a cross‐cultural context, using demographically heterogeneous samples. Study 2 recruited a new sample of 485 Americans and Canadians and examined their profiles on measures of social orientation and cognitive style twice, one month apart, to assess the stability of individual profiles using these variables.ResultsDespite finding typical cross‐cultural differences, Study 1 demonstrated negligible correlations both among measures of social orientation and among measures of cognitive style. Study 2 demonstrated stable intraindividual behavioral profiles across measures capturing idiosyncratic patters of social orientation and cognitive style, despite negligible correlations among the same measures.ConclusionThe results provide support for the behavioral profile approach to conceptualizing social orientation and cognitive style, highlighting the need to assess intraindividual stability of psychological constructs in cross‐cultural research.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/162694/2/jopy12536_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/162694/1/jopy12536.pd

Villages and Urbanization

In this article comments by politician Boris Johnson and economist Edward Glaeser exemplify narratives of global urbanization that portray rural villages as redundant and perpetuate outdated notions of urban–rural division. Simultaneously, traditional urban–rural dialectics are distorted by divisive new urban projects like gated communities styled as villages. This paper argues for development models that acknowledge the vital environmental and economic roles played by rural villages, and opposes artificially created “villages” in cities. In so doing, alternative readings of rurality and villages by Rem Koolhaas, Brazilian land reformers, Mahatma Gandhi, and critics of contemporary Indian literature and urbanism are considered

Performance evaluation and optimisation of post combustion CO2 capture processes for natural gas applications at pilot scale via a verified rate-based model

CO2 absorption based on chemical reactions is one of the most promising technologies for post combustion CO2 capture (PCC). There have been significant efforts to develop energy efficient and cost effective PCC processes. Given that PCC is still maturing as a technology, there will be a continuing need for pilot scale facilities to support process optimisation, especially in terms of energy efficiency. Pilot scale PCC facilities, which are usually orders of magnitude smaller than those that will be used in future in large scale fossil power plants, make it possible to study details of the PCC process at an affordable scale. However, it is essential that pilot scale studies provide credible data, if this is to be used with confidence to envisage the future large-scale use of the PCC process, especially in terms of energy consumption. The present work therefore establishes and experimentally verifies (using a representative pilot plant as a case study) procedures for analysing the energy performance of a pilot scale amine based CO2 capture plants, focusing on natural gas fired applications. The research critically assesses the pilot plant’s current energy performance, and proposes new operating conditions and system modifications by which the pilot plant will operate more efficiently in terms of energy consumption. The methodology developed to assess and improve the energy performance of the PCC process is applicable, with appropriate inputs, to other plants of this type that employs aqueous 30 wt. % monoethanolamine (MEA) solution as the solvent. A rate based model of the post combustion CO2 capture process using an aqueous solution of 30 wt. % MEA as the solvent was developed in Aspen Plus® V.8.4, and verified using the results of experimental studies carried out using the UK Carbon Capture and Storage Research Centre / Pilot-scale Advanced Capture Technology (UKCCSRC/PACT) pilot plant, as a representative pilot-scale capture plant, and employed for parametric sensitivity studies. Several parameters have been identified and varied over a given range of lean solvent CO2 loading to evaluate their effects on the pilot plant energy requirement. The optimum lean solvent CO2 loading was determined using the total equivalent work concept. Results show, for a given packing material type, the majority of energy savings can be realised by optimising the stripper operating pressure. To some extent, a higher solvent temperature at the stripper inlet has the potential to reduce the regeneration energy requirement. A more efficient packing material, can greatly improve the pilot plant overall energy and mass transfer efficiency

The Role of Historical Narrative in Biblical Thought:the Tendencies Underlying Old Testament Historiography

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68403/2/10.1177_030908928100602102.pd